Technical field

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United States of America Patent

PATENT NO 6803054
APP PUB NO 20030203022A1
SERIAL NO

10453422

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried. The tablet in the present invention is to provide stability against moisture at preserved, because the amorphous sugar changed to the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process. The tablet in the present invention is to further provide a design for the pharmaceutical preparation with respect to the stability of a drug, because the tablet is manufactured by one kind of a sugar and an amorphous sugar. Furthermore, the tablet in the present invention is to provide a production process by utilizing a common granulating machine and by utilizing a common tablet machine.

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First Claim

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INCTOKYO JAPAN

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kajiyama, Atsushi Yaizu, JP 10 165
Masuda, Yoshinori Yaizu, JP 43 461
Mizumoto, Takao Yaizu, JP 16 372
Nyshadham, Janaki Ram Palo Alto, CA 5 71
Yanagisawa, Masahiro Yaizu, JP 87 1139

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