Use of .DELTA.5-androstene-3.beta.-OL7,17-dione in the treatment of arthritis
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United States of America Patent
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Sep 21, 2004
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N/A
app pub date -
Nov 27, 2000
filing date -
Nov 19, 1997
priority date (Note) -
Expired
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Abstract
Arthritis can be treated by administering therapeutic amounts of .DELTA.5-androstene-3.beta.-ol-7,17-dione and metabolizable precursors thereof, such a .DELTA.5-androstene-3.beta.-acetoxy-7,17-dione, which are readily metabolized in vivo to .DELTA.5-androstene-3.beta.-ol-7,17-dione but are not appreciably metabolizable in vivo to androgens, estrogens or dehydroepiandrosterone. Such treatment can be prophylactic, ameliorative or curative in nature.
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