Process for producing amine derivatives
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United States of America Patent
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Aug 31, 2004
Grant Date -
Jul 24, 2003
app pub date -
Oct 1, 2002
filing date -
Apr 3, 2000
priority date (Note) -
Expired
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Abstract
This invention provides a convenient and industrially advantageous process producing amine derivatives having the action of inhibiting the secretion and accumulation of amyloid .beta. protein. ##STR1## In Compound (I), the ether linkage is selectively cleaved without cleaving the amide linkage present in the same molecule and tertiary amines are not converted into quaternary salts, and thus Amine Derivative (V) with good qualities having the action of inhibiting the secretion and accumulation of amyloid .beta. protein can be obtained in high yield.
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