Compositions for inhibiting the aggregation pathway of .alpha.-synuclein
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United States of America Patent
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Aug 24, 2004
Grant Date -
Oct 17, 2002
app pub date -
Jul 9, 2001
filing date -
Jul 7, 2000
priority date (Note) -
Expired
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Abstract
The present invention provides methods of determining aggregation of .alpha.-synuclein, which are a hallmark of Lewy body diseases such as Parkinson's disease. Also disclosed are inhibitors of the aggregation, including magnesium and .alpha.-synuclein binding peptides. The inhibitors are useful in the treatment of Lewy body diseases.
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