2-alkyl-5-halogen-pent-4-ene carboxylic acids and their production
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United States of America Patent
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Aug 17, 2004
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N/A
app pub date -
Jan 29, 2002
filing date -
Jul 29, 1999
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Expired
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Abstract
Compounds of formula I in the form of their racemates or enantiomers, ##STR1## preferably compounds of formula Ia ##STR2## wherein R.sub.4 is C.sub.1 -C.sub.6 alkyl, Z is chlorine, bromine or iodine, and X is --OH, chloride, bromide or iodide, or X forms an ester group with the carbonyl substituent, as well as salts of carboxylic acids. The compounds are valuable intermediates for the propagation of .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanecarboxamides, which exhibit renin-inhibiting properties and could be used as antihypertensive agents in pharmaceutical preparations.
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