Methods of identifying and determining the effectiveness of therapeutic processes or agents for the treatment of schizophrenia and related disorders
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United States of America Patent
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Aug 10, 2004
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app pub date -
Apr 14, 2000
filing date -
Apr 8, 1997
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Abstract
Methods for detecting schizophrenia or related neuropsychiatric disorders based on modifications of the contribution of the D.sub.4 receptor to phospholipid methylation levels are described herein. Individuals with schizophrenia or related neuropsychiatric disorders have a deficiency in phospholipid methylation activity compared with normal individuals. Methods for screening therapeutic processes or agents for use in treatment of schizophrenia or related neuropsychiatric disorders are also described.
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