Lipodepsipeptide antibiotics and methods of preparation
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United States of America Patent
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Jul 27, 2004
Grant Date -
Dec 4, 2003
app pub date -
May 10, 2002
filing date -
May 10, 2002
priority date (Note) -
Expired
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Abstract
Novel cyclodepsipeptide intermediates have been prepared from the A21978 complex and used to synthesize new lipodepsipeptide antibiotics. The three intermediates can be readily derivatized to give new families of antibiotics that have potent antibacterial activity against gram positive bacteria.
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