Plasma cross-linked hydrophilic coating
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United States of America Patent
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Jul 20, 2004
Grant Date -
May 15, 2003
app pub date -
Sep 27, 2002
filing date -
Sep 28, 2001
priority date (Note) -
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Abstract
A method for making a hydrophilic and lubricious coating, the coating so made and a medical device including such coating, wherein the coating includes a hydrophilic polymeric unit layer cross-linked with a plasma deposited double bond monomer. The hydrophilic polymeric unit can include ethylene oxide with one or more primary or secondary alcohol groups or glycosaminoglycans such as hyaluronic acid, and the double bond monomer includes monomers containing at least one double bond, preferably a C.dbd.C, C.dbd.N or C.dbd.O bond, including N-trimethylsilyl-allylamine, ethylene, propylene and allyl alcohol. The invention also provides products containing such coatings and their uses in medical, pharmaceutical and cosmetic applications.
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