Process for dehydrogenation of azaandrostane compounds
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United States of America Patent
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Jul 13, 2004
Grant Date -
Nov 20, 2003
app pub date -
May 6, 2003
filing date -
May 10, 2002
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Abstract
The invention relates to a process for the production of compounds of general formula (I), wherein R.sub.1 is a --NH-tert-butyl group or a 4-methyl-piperidino group, by bioconversion of compounds of general formula (II), wherein R.sub.1 is as described above, using a biocatalyst having steroid-.DELTA..sup.1 -dehydrogenase enzyme activity, wherein the activity of the enzyme needed for the bioconversion is produced by induction. ##STR1##
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