Inhibitors of cyclin-dependent kinases, compositions and uses related thereto
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United States of America Patent
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Jun 22, 2004
Grant Date -
Aug 28, 2003
app pub date -
Dec 17, 2002
filing date -
Dec 3, 2001
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Expired
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Abstract
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.
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