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Abstract

The present invention relates to compounds of the formula ##STR1## wherein R.sub.1 independently represents one or more, same or different substituents selected from the group consisting of halogen, hydroxy, mercapto, trifluoromethyl, amino, (C.sub.1 -C.sub.3)alkyl, (C.sub.2 -C.sub.3)olefinic group, (C.sub.1 -C.sub.3)alkoxy, (C.sub.1 -C.sub.3)alkylthio, (C.sub.1 -C.sub.6)alkylamino, (C.sub.1 -C.sub.3)alkoxycarbonyl, cyano, carbamoyl, phenyl and nitro, provided that when R.sub.1 represents one substituent, it is in the ortho position, and when R.sub.1 represents more than one substituent, at least one R.sub.1 substituent is in the ortho position; R.sub.2 is one substituent in the ortho position, said substituent being selected from the group consisting of hydrogen, halogen, hydroxy, mercapto, trifluoromethyl, amino, (C.sub.1 -C.sub.3)alkyl, (C.sub.2 -C.sub.3)olefinic group, (C.sub.1 -C.sub.3)alkoxy, (C.sub.1 -C.sub.3)alkylthio, (C.sub.1 -C.sub.6)alkylamino, (C.sub.1 -C.sub.3)alkoxycarbonyl, cyano, carbamoyl, phenyl and nitro; R.sub.3 represents hydrogen, halogen, hydroxy, mercapto, trifluoromethyl, amino, (C.sub.1 -C.sub.3)alkyl, (C.sub.2 -C.sub.3)olefinic group, (C.sub.1 -C.sub.3)alkoxy, (C.sub.1 -C.sub.3)alkylthio, (C.sub.1 -C.sub.6)alkylamino, (C.sub.1 -C.sub.3)alkoxycarbonyl, phenyl, cyano, carboxy, or carbamoyl; R.sub.4 represents hydrogen, (C.sub.1 -C.sub.3)alkyl, or allyl. The compounds are valuable in the human and veterinary therapy.

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First Claim