Method and apparatus for estimating degree of neuronal impairment in brain cortex
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United States of America Patent
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May 25, 2004
Grant Date -
Aug 8, 2002
app pub date -
Nov 27, 2001
filing date -
Dec 18, 2000
priority date (Note) -
Expired
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Abstract
A proper frequency component of EEG is selected so that its scalp potential becomes smooth in a normal subject. When the brain function is impaired, non-uniformity of neuronal activity is detected in spatial as well as temporal fluctuations in the observed scalp potential of properly filtered EEG (usually the alpha component). The statistical parameters derived from dipolarity values of such a properly selected EEG component determine the state of the brain, in which whether the subject is normal or demented is judged in the early stage of dementia by comparing the obtained parameters with their threshold values. This invention presents a reliable, inexpensive, easy-to-handle and non-invasive method for sensitive screening of dementia and monitoring progress of dementia which also allows optimizing medication and treatment for dementia.
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