Ligand for vascular endothelial growth factor receptor
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United States of America Patent
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May 11, 2004
Grant Date -
May 16, 2002
app pub date -
Feb 2, 2001
filing date -
Feb 4, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to compositions comprised of a peptide ligand or derivatives thereof that are capable of specific binding to the high affinity receptor-1 of vascular endothelial growth factor (VEGF) and structure similar receptors. The invention further provides a peptide ligand or derivatives thereof that are capable of inhibiting angiogenesis induced by VEGF. The present invention also provides a method for treatment or diagnosis of disease associated with angiogenesis in a patient in need of therapy comprising administering to the patient an effective amount of the pharmaceutical composition of the present invention and a pharmaceutical acceptable carrier.
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