Purification of plasmid DNA of pharmaceutical quality
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United States of America Patent
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May 4, 2004
Issued Date -
N/A
app pub date -
Sep 15, 1998
filing date -
Mar 21, 1996
priority date (Note) -
Expired
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Abstract
The invention is directed to a process for purifying double-stranded DNA, comprising using ceramic hydroxyapatite column chromatography. The invention is also directed to a purified recombinant plasmid DNA composition, comprising a chromosomal DNA content that is less than or equal to 0.01% as well as to a composition comprising DNA prepared by the foregoing process.
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