Methods of modulating serine/threonine protein kinase function with 5-azaquinoxaline-based compounds

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United States of America Patent

PATENT NO 6727252
SERIAL NO

09688199

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Abstract

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The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with 5-azaquinoxaline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to 5-azaquinoxaline compounds and pharmaceutical compositions comprising these compounds.

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Patent Owner(s)

Patent OwnerAddress
ZENTARIS AG60314 FRANKFURT/MAIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
App, Harald San Francisco, CA 15 524
Kutscher, Bernhard Maintal, DE 52 685
McMahon, Gerald San Francisco, CA 82 2488
Weinberger, Heinz Sulzbach/Ts, DE 8 185

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