Importance

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Abstract

Described herein are compounds useful in the treatment of migraine, which have the general formula: ##STR1## wherein: W is a CH group or a N atom; Z is N or C--R4; B and D are selected independently from CH and N, with the proviso that at least one of B and D is CH and with the further proviso that one of B and D can represent N only when W and Z are both other than N; A is a group of Formula II, III or IV, such that group A contains at least 1 N atom; NR7 is either --NH--or --N.dbd.; {character pullout} is a single or double bond; X is a N atom, a CH group or a C(OH) group when {character pullout} is a single bond; or, when {character pullout} is a double bond, a C atom; Y is an NH, N-alkyl, N-benzyl or CH.sub.2 group; U and V each represent a N atom or a CH group, with the proviso that both cannot be N; a and b are, independently, 0 or 1; c is an integer from 0 to 3; d is an integer from 1 to 3; e is an integer from 1 to 2; f is an integer from 0 to 3; g is an integer from 3 to 6 and h is an integer from 2 to 3; such that the sum of c and d is at least 2 and the sum of e and f is at least 2; and salts and solvates thereof.

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First Claim