Polypeptides having .alpha.-hydroxy-.gamma.-carboxymuconic acid-.epsilon.-semialdehyde dehydrogenase activity
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United States of America Patent
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Apr 6, 2004
Grant Date -
Jul 25, 2002
app pub date -
Oct 24, 2001
filing date -
Jul 17, 1998
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Abstract
.alpha.-Hydroxy-.gamma.-carboxymuconic acid-.epsilon.-semialdehyde dehydrogenase, a gene encoding the enzyme, a recombinant vector containing the gene and a transformant carrying the gene, and processes for producing the enzyme and 2-pyrone-dicarboxylic acid by using the transformant. Use of the transformant can produce .alpha.-hydroxy-.gamma.-carboxymuconic acid-.epsilon.-semialdehyde dehydrogenase in a large amount, thereby permitting industrial production of 2-pyrone-4,6-dicarboxylic acid.
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