Spherical microparticles containing linear polysaccharides
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United States of America Patent
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Mar 9, 2004
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N/A
app pub date -
Apr 14, 2000
filing date -
Aug 28, 1997
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Abstract
Microparticles with a uniform spherical shape and a very narrow size distribution are described. They consist wholly or partly of a linear water-insoluble polysaccharide, preferably of 1,4-.alpha.-D-polyglucan, and may contain other, in particular biodegradable, polymers and/or active substances. They are suitable inter alia for the controlled delivery of active substances. They are prepared by dissolving 1,4-.alpha.-D-polyglucan or the polysaccharide in a solvent, introducing the solution into a precipitant, cooling the mixture and removing the particles formed.
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