Prodrugs activated by targeted catalytic proteins

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United States of America Patent

PATENT NO 6702705
SERIAL NO

08392407

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.

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Patent Owner(s)

Patent OwnerAddress
WELLSTAT BIOCATALYSIS LLC930 CLOPPER ROAD GAITHERSBURG MD 20878

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Casadei, Jan M Bethesda, MD 4 17
Kamireddy, Balreddy Rockville, MD 16 73
Kenten, John Gaithersburg, MD 40 117
Martin, Mark T Germantown, MD 44 898
Massey, Richard J Rockville, MD 48 1255
Napper, Andrew D Natick, MA 14 60
Simpson, David M Adelphia, MD 21 239
Smith, Rodger Jefferson, MD 17 285
Titmas, Richard C Rockville, MD 14 113
von, Borstel Reid Potomac, MD 13 159
Williams, Richard O Potomac, MD 16 274

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