Anticancer agents
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United States of America Patent
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Jan 27, 2004
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N/A
app pub date -
Aug 2, 2002
filing date -
Sep 30, 1999
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Abstract
Disclosed herein is a method for suppressing the growth of cancer cells in a mammal in need of such treatment comprising administering to said mammal a cancer cell suppressing amount of a diphenylmethylpiperazine represented by the following general formula [1]: ##STR1## wherein R represents: ##STR2## or a pharmaceutically acceptable salt thereof. Compared with conventional anticancer agents, these agents are less toxic and exert an excellent carcinostatic effect on various solid cancers. Moreover, these anticancer agents inhibit the proliferation of fibroblasts, which makes them efficacious against pulmonary fibrosis and proliferative keloid lesions.
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