Specific inhibitors of hyaluronidase 2, and methods of identifying and using same

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United States of America Patent

PATENT NO 6682904
SERIAL NO

10222032

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods for identifying a hyaluronidase 2 (HYAL2) specific inhibitor, which selectively inhibits HYAL2 activity, but does not substantially affect the activity of non-inflammatory hyaluronidases, are provided. Also provided are HYAL2 specific inhibitors obtained using such a method. In addition, methods for ameliorating an inflammatory disorder or vasculitis condition by specifically inhibiting HYAL2 is provided.

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Patent Owner(s)

Patent OwnerAddress
HALOZYME INC11388 SORRENTO VALLEY ROAD SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frost, Gregory I Solana Beach, CA 67 4300

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