Production of optically active 2-substituted tetrahydropyran-4-ones

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United States of America Patent

PATENT NO 6680183
APP PUB NO 20020048797A1
SERIAL NO

09870587

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Abstract

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Optically active 2-substituted tetrahydropyran-4-ols or esters thereof may be prepared using esterases or hydrolases from the corresponding racemic mixtures of esters or alcohols. This provides a route to the corresponding optically active ketones. The racemic mixtures are preferably in the cis-form. such mixtures may be produced by reacting but-3-ene-1-ol with an aldehyde in the presence of an acid.

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Patent Owner(s)

Patent OwnerAddress
AVECIA LIMITEDHEXAGON HOUSE BLACKEY MANCHESTER M9 8ZS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holt, Robert Antony Billingham, GB 11 41
Rigby, Stuart Richard Billingham, GB 3 2
Waterson, David Macclesfield, GB 47 286

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