Non-peptidic cyclophilin binding compounds and their use
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United States of America Patent
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Jan 13, 2004
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app pub date -
Sep 7, 2000
filing date -
Sep 8, 1999
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Abstract
The invention relates to non-peptidic compounds that possess bioactive properties, such as the ability to protect neuronal cells from otherwise lethal treatments or the ability to promote the growth or regeneration of neuronal cells. In part, the invention provides compounds that interact with or bind to a cyclophilin and compounds that have activity towards neuronal cells. Methods for using the compounds, such as administering them to cells or animals or using them to treat neurodegenerative conditions, are specifically included.
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