Established cell line of microglia
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United States of America Patent
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Jan 6, 2004
Grant Date -
Aug 22, 2002
app pub date -
Mar 8, 1999
filing date -
Mar 5, 1997
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Abstract
The present invention relates to an established cell line of microglia having the following properties: (a) form: having a macrophage-like or globular form in the presence of granulocyte-macrophage colony-stimulating factor. and in the absence of said factor, a branched form similar to branched microglia present in the brain, or both of the above forms; (b) functional characteristics: having specific affinity for the brain, and having a strong phagocytic ability; and (c) cell growth ability: growing depending on granulocyte-macrophage colony-stimulating factor. In particular, cell lines FERM BP-7061 and FERM BP-7062.
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