Electrophoretic tag reagents comprising fluorescent compounds

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United States of America Patent

PATENT NO 6673550
SERIAL NO

10008495

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Abstract

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Electrophoretic probes comprising fluorescent compounds as detection groups and mobility modifiers are disclosed for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. In one embodiment, detection involves the release of identifying tags as a consequence of target recognition. Target antiligands are contacted with a set of e-tag probes and the contacted antiligands are treated with a selected cleaving agent resulting in a mixture of e-tag reporters. Typically, uncleaved or partially cleaved e-tag probes are removed and the mixture of e-tag reporters is separated by any technique that provides for separation by mass or mass to charge ratio and the like and detected to provide for target identification.

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Patent Owner(s)

Patent OwnerAddress
VIROLOGIC INC345 OYSTER POINT BLVD MOUNTAIN VIEW CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hernandez, Vincent Brookdale, CA 17 143
Matray, Tracy San Lorenzo, CA 78 1798
Singh, Sharat San Jose, CA 279 5843

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