Separation of micromolecules
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United States of America Patent
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Dec 9, 2003
Grant Date -
Oct 17, 2002
app pub date -
Apr 13, 2001
filing date -
Apr 14, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An apparatus and method for the separation of molecules having a molecular mass from about 200 to 5000 Da, particularly micromolecules having a molecular mass of less than 5000 Dalton. The apparatus contains an anode, a cathode disposed between the anode and the separation membrane that defines a first interstitial volume therebetween. A first restriction membrane disposed between the anode and the separation membrane defines a second interstitial volume therebetween. Upon application of the voltage potential, a selected separation product is removed from the sample constituent through the separation membrane, and provided to the other of the first and second interstitial volumes.
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