Therapeutic methods and compositions involving isoflavones

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United States of America Patent

PATENT NO 6649648
SERIAL NO

09254026

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by general formula (I), in which Z is H, R.sub.1 is H, or R.sub.A CO where R.sub.A is C.sub.1-10 alkyl or an amino acid, R.sub.2 is H, OH, or OR.sub.B where R.sub.B is an amino acid, or COR.sub.A where R.sub.A is as previously defined, W is H, A is H or OH, and B is selected from (a), (b), (c), or W is H, and A and B taken together form a six-membered ring selected from (d), or W, A and B taken with the groups with which they are associated comprise (e), or W and A taken together with the groups with which they are associated comprise (f) and B is (g) wherein R.sub.3 is H, COR.sub.A where R.sub.A is as previously defined, CO.sub.2 R.sub.C where R.sub.C is C.sub.1-10 alkyl, or COR.sub.B where R.sub.B is as previously defined, R.sub.4 is H, COR.sub.D where R.sub.D is H, OH, C.sub.1-10 alkyl or an amino acid, CO.sub.2 R.sub.C where R.sub.C is as previously defined, COR.sub.E where R.sub.E is H, C.sub.1-10 alkyl or an amino acid, COOH, COR.sub.C where R.sub.C is as previously defined, or CONHR.sub.E where R.sub.E is as previously defined, R.sub.5 is H, CO.sub.2 R.sub.C where R.sub.C is as previously defined, or COR.sub.C OR.sub.E where R.sub.C and R.sub.E are as previously defined, and where the two R.sub.5 groups are attached to the same group they are the same or different, R.sub.6 is H or hydroxy C.sub.1-10 alkyl, X is preferably O, but may be N or S, and Y is (h) where R.sub.7 is H, or C.sub.1-10 alkyl. ##STR1## ##STR2##

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Patent Owner(s)

Patent OwnerAddress
MARSHALL EDWARDS INC11975 EL CAMINO REAL SUITE 101 SAN DIEGO CA 92130

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Joannou, George Eustace New South Wales, AU 13 150
Kelly, Graham Edmund New South Wales, AU 48 637

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