Beaded polyethylene glycol-based resins

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United States of America Patent

PATENT NO 6642334
APP PUB NO 20030050415A1
SERIAL NO

09901343

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Abstract

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Described herein is a pentaalkyldisiloxane containing polymeric surfactant prepared by the copolymerization of an alkoxypolyoxyalkylenyl acrylate and an acrylate containing a pentaalkyldisiloxane group. A method for preparing beaded polyethylene glycol-based resins in silicone oil in the presence of a polymeric surfactant containing a pentaalkyldisiloxane group is also described. The average bead size can be controlled by varying the stirring rate, the polymerization temperature, the amount of surfactant, the type of solvent, and the amount of solvent. The surfactant does not interfere with the polymerization and can be removed together with residual silicone oil by a simple washing procedure. The resins can be used, for example, as a support for solid phase organic synthesis, as a chromatographic resin, as a resin for solid phase MAS-NMR spectroscopy, and as a carrier for drug molecules, various reagents, or scavengers.

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Patent Owner(s)

Patent OwnerAddress
CARLSBERG A/SDANMAI VAL BE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gro, slashedtli Morten Oslo, NO 1 1
Meldal, Morten Peter Frederiksberg, DK 3 22

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