Crustacean antimicrobial peptides
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United States of America Patent
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Nov 4, 2003
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N/A
app pub date -
Apr 12, 2000
filing date -
Jul 21, 1997
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Expired
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Abstract
The invention concerns antimicrobial peptides obtained from penaeid prawns having the following characteristics: a molecular mass of about 5 to 7 kDa; a pHi not less than 9; an N-terminal portion comprising a region (A) of about 15 to 25 amino acids rich in proline; and a C-terminal portion comprising a region (B) of about 20 to 30 amino acids and containing 6 cysteine residues forming three intramolecular disulfide bonds. The invention also concerns the nucleic acid sequences coding for said peptides and enabling their production by genetic engineering.
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