Cysteine protease inhibitors
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United States of America Patent
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Oct 21, 2003
Grant Date -
N/A
app pub date -
Jan 30, 2002
filing date -
Jul 31, 1999
priority date (Note) -
Expired
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Abstract
This invention relates to derivatives of alpha-amino acid amides, to pharmaceutical compositions containing such compounds, and to their use in medicine as inhibitors of cysteine proteases, particularly the cathepsins. A compound of formula (I) is described or a pharmaceutically acceptable salt, hydrate or solvate thereof. Pharmaceutically acceptable salts of the compounds of this invention include the sodium, potassium, magnesium, calcium, hydrogen chloride, tartaric acid, succinic acid, fumaric acid and p-toluenesulfonic acid salts. ##STR1##
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