Fusobacterium necrophorum vaccine and method for making such vaccine
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United States of America Patent
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Oct 14, 2003
Grant Date -
Aug 22, 2002
app pub date -
Sep 29, 1999
filing date -
Sep 29, 1999
priority date (Note) -
Expired
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Abstract
The present invention relates to a method of producing a vaccine for the prevention of F. necrophorum bacterial infections, comprising isolating the F. necrophorum bacteria from a bovine species, growing the bacteria in a suitable growth medium for a period equal to between about 10 hours and about 18 hours so as to achieve a bacterial population equal to at least 1.times.10.sup.5 CFU/ml, terminating the growth, and using a whole cell culture to form the vaccine. Additionally, the present invention relates to the vaccine comprised of a killed whole cell population of the F. necrophorum bacteria taken from a bovine. The present invention further relates to a method for preventing footrot and liver abscesses caused by F. necrophorum bacteria.
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