5-HT3 receptor assay using transgenic mammal
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United States of America Patent
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Oct 7, 2003
Grant Date -
Dec 20, 2001
app pub date -
Jun 26, 2001
filing date -
Oct 15, 1997
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Expired
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Abstract
The invention relates to transgenic mammals characterized by 5-HT.sub.3 receptor over-expression in the central nervous system (CNS). The mammals have particular utility as models for studying the role of 5-HT.sub.3 receptors in the CNS, especially for the study of reward pathways for alcohol and other substances of abuse.
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