Method for identifying compounds for treatment of insulin resistance
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United States of America Patent
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Oct 7, 2003
Grant Date -
Nov 1, 2001
app pub date -
Feb 2, 2001
filing date -
Aug 10, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention features a method of identifying, evaluating or making a compound or agent, e.g., a candidate compound or agent, for treatment of a disorder characterized by insulin resistance. The method includes evaluating the ability of a compound or agent to bind IKK-.beta. or modulate IKK-.beta. activity, to thereby identify a compound or agent for the treatment of a disorder characterized by insulin resistance. The invention also features compounds for treating insulin resistance identified by such methods, and methods of treating a subject having a disorder characterized by insulin resistance by administering such agents.
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