Pharmaceutical formulation and its use
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United States of America Patent
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Oct 7, 2003
Grant Date -
N/A
app pub date -
Nov 9, 2000
filing date -
Nov 11, 1999
priority date (Note) -
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Abstract
The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the formulation exhibits a controlled in vitro release of the active ingredient in phosphate buffer at pH 6.8 of not less than about 80% after 18 hours, and after oral administration to a patient is capable of maintaining a substantially constant serum level of the active moiety or moieties for 24 hours. The invention also relates to the use of the pharmaceutical formulation for treating overactive bladder and gastrointestinal disorders.
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