Time-of-flight bacteria analyser using metastable source ionization
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United States of America Patent
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Sep 30, 2003
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N/A
app pub date -
Nov 28, 2000
filing date -
Nov 28, 2000
priority date (Note) -
Expired
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Abstract
For analyzing micro-organisms and other high-molecular weight species, a sample of the substance to be analyzed is prepared, placed in a pyrolyzer where it is pyrolyzed with a selected temperature program to provide pyrolyzed product of a high-dalton mass range. The product is ionized using metastable atoms which results in efficient ionization with little fragmentation. The metastable atoms are generated using a generator that provides a beam of metastable atoms which is basically free from ions. The ionized product is then analyzed using a high acquisition rate mass analyzer, such as a time-of-flight (TOF) analyzer.
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