Dual manifold system and method for fluid transfer
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United States of America Patent
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Sep 30, 2003
Grant Date -
N/A
app pub date -
Mar 4, 1999
filing date -
Mar 4, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A dual-manifold assembly is provided for the rapid, parallel transfer of liquid reagents from a microtiter plate to a solid state microelectronic device having biological sensors integrated thereon. The assembly includes aspiration and dispense manifolds connected by a plurality of conduits. In operation, the aspiration manifold is actuated such that the aspiration manifold is seated onto an array of reagent-filled wells of the microtiter plate. The wells are pressurized to force reagent through conduits toward the dispense manifold. A pressure pulse provided by a standard ink-jet printhead ejects nanoliter-to-picoliter droplets of reagent through an array of printhead orifices and onto test sites on the surface of the microelectronic device.
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