Benzopyrazone compounds, compositions thereof, and methods of treatment therewith

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United States of America Patent

PATENT NO 6620838
SERIAL NO

10125965

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Abstract

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Benzopyranone compounds having the following structure: ##STR1## wherein R.sub.1, X, Y and n are as defined here, are disclosed. The compounds of formula (I), wherein R.sub.1 is H, can be prepared by demethylation of the corresponding phenolic methyl ether. The compounds are useful for treating a bone-resorbing disease, cancer, arthritis or an estrogen-related condition such as breast cancer, osteoporosis and endometriosis.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhagwat, Shripad S San Diego, CA 45 1019
McKie, Jeffrey A San Diego, CA 11 155
Missbach, Martin Basil, CH 31 107
Renaud, Johanne Basil, CH 17 111

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