Processes and compositions for the production of chiral amino-nitriles
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United States of America Patent
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Aug 26, 2003
Grant Date -
Apr 3, 2003
app pub date -
Sep 28, 2001
filing date -
Sep 28, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Processes for the efficient production of chiral amino nitrites are disclosed. Generally, the processes include the esterification of the alcohol of a amino protected alcohol followed by nucleophilic substitution of the ester with a cyano group. In an exemplary embodiment the chiral amino nitrile produced is (R)-3-aminopentanenitrile.
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