2-n-substituted or unsubstituted-2-amino-5-methylpiperidine-3,4-diols and processes for the preparation thereof
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United States of America Patent
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Aug 26, 2003
Grant Date -
N/A
app pub date -
Aug 1, 2001
filing date -
Feb 2, 1999
priority date (Note) -
Expired
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Abstract
This invention relates to (2R,3S,4R,5R)-2-amino-5-methylpiperidine-3,4-diol or a (2S,3S,4R,5R)-2-N-substituted-2-amino-5-methylpiperidine-3,4-diol represented by the general formula (I): ##STR1## wherein R.sup.1 and R.sup.2 each are a hydrogen atom, or R.sup.1 is a hydrogen atom and R.sup.2 is a lower alkanoyl group or a lower .omega.-trihaloalkanoyl group, or R.sup.1 and R.sup.2 together denote phthaloyl group, and a pharmaceutically acceptable salt thereof. Said compound can be prepared from a (2S,3S,4R)-5-N-protected-2,3,4-O-tri-protected-5-aminopentane-1,2,3,4-tetraol by multi-steps of reactions.
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