Serine protease inhibitors
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United States of America Patent
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Aug 19, 2003
Issued Date -
N/A
app pub date -
Nov 16, 2001
filing date -
Nov 21, 1994
priority date (Note) -
Expired
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Abstract
Certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases, are prepared in various embodiments using Grignard reagents and alkyllithium reagents and various aldehydes to make oxadiazole, thiadiazole and triazole peptoid alcohols, which are then oxidized to the desired keto products.
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