A protective tote bag is for covering and carrying a briefcase of the type having a handle at the top and having a length, a height and a width defining a rectangular shape. The protective tote bag includes an enclosure which is formed of a protective fabric material and having two closed sides, two closed ends and a closed bottom defining a rectangular shape sufficiently large for accommodating the briefcase to be covered and with a closable opening along a top edge thereof. A support strap having a width corresponding to a minimum width of the briefcase to be covered is securely fastened as through stitching and along two ends extending around the bottom of the enclosure. A shoulder strap is securely fastened to the support strap at each end of the enclosure so that it extends above the closable opening at the top edge of the enclosure to form a loop which has a sufficient length for supporting the tote bag over a human being's shoulder.

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