Enrichment of dendritic cells from blood

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United States of America Patent

PATENT NO 6589526
APP PUB NO 20010023072A1
SERIAL NO

09774948

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Abstract

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A method for the enrichment of dendritic cells from the peripheral blood of a mammal is described. Peripheral blood having mononuclear cells from a mammal is provided. The mononuclear cells are separated from the peripheral blood. The mononuclear cells are separated into a first cell population having substantially lymphocytes and a second cell population having substantially myeloid cells. The myeloid cells are separated into a third cell population having substantially monocytes and a fourth cell population having substantially dendritic cells. Also described are purified dendritic cell populations, vaccine compositions and methods for the treatment of cancer using dendritic cells, and kits useful for the enrichment of dendritic cells from blood.

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Patent Owner(s)

Patent OwnerAddress
CENTER FOR BLOOD RESEARCHBOSTON MA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alper, Chester A Brookline, MA 4 71
Crawford, Keith D Boston, MA 25 479

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