Continuous process for the preparation of optically pure decahydroisoquinolinecarboxamide

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United States of America Patent

PATENT NO 6586597
SERIAL NO

09857566

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Abstract

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The present invention relates to a continuous process for the preparation of [3S-(3.alpha., 4a.beta., 8a.beta.)]-N-tert-butyl-decahydro-3-isoquinolinecarboxamide, an intermediate useful in the synthesis of compounds for the treatment of viral diseases, from the reduction of N-tert-butyl-1,2,3,4-tetrahydro-3(S)-isoquinolinecarboxamide with a noble metal catalyst supported on inorganic oxide carrier in a fixed bed reaction system, with a high optical yield.

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Patent Owner(s)

Patent OwnerAddress
SK BIOPHARMACEUTICALS CO LTDSEONGNAM-SI GYEONGGI-DO 13494

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Tae-Yun Taejon, KR 38 273
Kwak, Byoung-Sung Taejon, KR 1 0
Lee, In-Woo Taejon, KR 2 6
Oh, Seung-Hoon Taejon, KR 7 259
Park, Sang-Hoon Taejon, KR 116 870

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