Methods for solid phase combinatorial synthesis of integrin inhibitors
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United States of America Patent
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Jul 1, 2003
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N/A
app pub date -
Apr 13, 2000
filing date -
Apr 14, 1999
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Expired
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Abstract
Compounds of the formula ##STR1## are useful in the treatment of various disorders including, but not limited to, cancer (tumor metathesis, tumorgenesis/tumor growth), angiogenesis (as in cancer, diabetic retinopathy, rheumatoid arthritis), restenosis (following balloon angioplasty or stent implantation), inflammation (as in rheumatoid arthritis, psoriasis), bone diseases (osteopenia induced by bone metastases, immobilization and glucocortocoid treatment, periodontal disease, hyperparathyroidism and rheumatoid arthritis), and as antiviral agents. Novel method of making compounds of formula I are also provided.
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