Use of Salmonella vectors for vaccination against helicobacter infection
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United States of America Patent
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Jul 1, 2003
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N/A
app pub date -
Nov 1, 1999
filing date -
Apr 30, 1998
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Abstract
The invention provides a method of immunization against Helicobacter, involving mucosal administration of an attenuated Salmonella vector including a nucleic acid molecule encoding a Helicobacter antigen, and parenteral administration of a soluble Helicobacter antigen, co-administered with a suitable parenteral adjuvant. Also provided by the invention are attenuated Salmonella vectors for use in this method.
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