Method for purifying thrombin substrate and/or inhibitors or method for eliminating the same
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United States of America Patent
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Jun 24, 2003
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N/A
app pub date -
Jul 21, 2000
filing date -
Oct 23, 1997
priority date (Note) -
Expired
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Abstract
A method for the refinement of a thrombin substrate, characterized by comprising therein a step of affinity chromatography formed by using an affinity adsorbent having as a ligand a thrombin or thrombin analogue deprived of nucleophilicity (activity) without causing stereostructure to the linkage with a substrate is disclosed.
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