Compositions and uses of dictyostatin compounds
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United States of America Patent
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Jun 10, 2003
Grant Date -
Dec 27, 2001
app pub date -
Feb 26, 2001
filing date -
Feb 24, 2000
priority date (Note) -
Expired
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Abstract
Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.
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