Use of dopamine receptor antagonists in palliative tumor therapy
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United States of America Patent
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Jun 10, 2003
Issued Date -
N/A
app pub date -
Jun 23, 2000
filing date -
Dec 6, 1996
priority date (Note) -
Expired
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Abstract
The side effect of decrease in body weight caused by the alkylphosphocholines such as miltefosine can be antagonized by certain acetylcholine receptor antagonists such as domperidone and pimozide. The combination of alkylphosphocholine plus the antagonist does not have any effect on the anti-tumor action of the alkylphosphocholine. The combination also caused no new side effects in the animals.
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