Magnetic resonance imaging
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United States of America Patent
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Jun 3, 2003
Grant Date -
N/A
app pub date -
May 18, 2000
filing date -
May 19, 1999
priority date (Note) -
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Abstract
A method of magnetic resonance investigation of a sample by (i) reacting ortho-deuterium enriched hydrogen with a hydrogenatable MR imaging agent precursor to produce a hydrogenated (i.e. deuterated) MR imaging agent; (ii) optionally, subjecting the hydrogenated MR imaging agent to a low magnetic field;(iii) administering the hydrogenated MR imaging agent to the sample; (iv) exposing the sample to radiation of a frequency selected to excite nuclear spin transitions of selected non-zero nuclear spin nuclei in said hydrogenated MR imaging agent; (v) detecting magnetic resonance signals of the selected non-zero nuclear spin nuclei from the sample; and (vi) optionally, generating an image or biological functional data or dynamic flow data from the detected signals.
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