Process for manufacturing simvastatin and novel intermediates thereof

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United States of America Patent

PATENT NO 6573385
SERIAL NO

10194126

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Abstract

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The present invention provides intermediates of formula IIb and IIc useful for the preparation of Simvastatin: ##STR1## wherein R.sub.1 and R.sub.2 are each independently an alkyl, heteroalkyl, aryl or heteroaryl moiety, or R.sub.1 and R.sub.2, taken together, form a heterocyclic moiety containing 5-8 atoms; wherein each of the foregoing alkyl and heteroalkyl moieties may be linear or branched, substituted or unsubstituted, cyclic or acyclic or saturated or unsaturated, and each of the foregoing heterocyclic, aryl and heteroaryl moieties may be substituted or unsubstituted.

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Patent Owner(s)

Patent OwnerAddress
BIOCON INDIA LIMITEDHEBBAGODI BANGALORE 561 229

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Acharya, Poornaprajna Karnataka, IN 5 12
Mathew, Joy Karnataka, IN 11 49
Sambasivam, Ganesh Bangalore, IN 13 31
Sridharan, Madhavan Karnataka, IN 14 53

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